[Comparative analysis of fertile and infertile cycles during stimulation of ovulation with pergonal in patients with hypo- gonadotropic amenorrhea].

Abstract

A comparative assessment of variations in sex hormone levels and echographic parameters of fertile and infertile cycles was carried out in patients with gonadotrophic deficiency during pergonal induction of the ovulation. It was demonstrated that 83% of the infertile cycles were the first stimulation cycles. Basic differences were identified in the variation of sex hormone levels and echographic parameters of target organs between the fertile and infertile cycles. It is concluded that the first ovulation-induction course should be regarded as a preventive or preparatory one, where an optimum drug dosage is adjusted while the gonads and target organs are getting ready for the ovulation.

• Authors: I A Manuilova, E I Sotnikova, R N Shchedrina, I G Torganova, T A Nazarenko, B I Zykin
• Journal: Akusherstvo i ginekologiia (Akush Ginekol (Mosk)) Issue 10 Pg. 14-8 (Oct 1989) ISSN: 0300-9092 [Print] Russia (Federation)
• Vernacular Title: Sravnite'lnyĭ analiz ferti'lnykh i neferti'lnykh tsiklov pri stimuliatsii ovuliatsii pergonalom u patsientok s gipogonado- tropnoĭ amenoreeĭ.
• PMID: 2515765 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Chorionic Gonadotropin
• Fertility Agents, Female
• Menotropins

Topics

• Amenorrhea (drug therapy, physiopathology)
• Anovulation (drug therapy, physiopathology)
• Chorionic Gonadotropin (administration & dosage)
• Female
• Fertility (drug effects, physiology)
• Fertility Agents, Female
• Humans
• Menotropins (administration & dosage, deficiency, therapeutic use)
• Menstrual Cycle (drug effects, physiology)
• Ovulation (drug effects, physiology)
• Ovulation Induction