Abstract | OBJECTIVE: METHODS: This prospective study was conducted in 380 elderly individuals, including 135 patients with MetS, 142 patients with metabolic disturbance (MetD), and 103 healthy elderly individuals (control group). Waist-hip ratio, waist circumference, waist-height ratio, body mass index (BMI), fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), low-density lipoprotein cholesterol ( LDL-C), triglycerides (TG), high-density lipoprotein (HDL-C), systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure and cystatin C were measured and their mutual relations were analyzed. RESULTS: The higher the MetS scores, the higher the serum cystatin C concentration in these patients. Serum cystatin C concentration was closely related to waist-hip ratio, waist circumference, waist-height ratio, BMI, TG, FPG, and blood pressure, not related to LDL-C levels, and negatively correlated with HDL-C levels. Logistic regression analysis indicated that cystatin C, waist-height ratio, waist circumference, FPG, TG, SBP and pulse pressure were significantly associated with MetS (OR between cystatin C and MetS 2.164, 95% CI 1.136-8.259). CONCLUSION:
Cystatin C was significantly associated with MetS in the elderly. As MetS scores rose, serum cystatin C levels increased.
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Authors | Ping Liu, Shujian Sui, Dongling Xu, Xiaowei Xing, Caixia Liu |
Journal | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
(Rev Port Cardiol)
2014 Jul-Aug
Vol. 33
Issue 7-8
Pg. 411-6
ISSN: 2174-2030 [Electronic] Portugal |
PMID | 25155006
(Publication Type: Journal Article)
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Copyright | Copyright © 2013 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved. |
Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Cystatin C
(blood)
- Female
- Humans
- Male
- Metabolic Syndrome
(blood)
- Middle Aged
- Prospective Studies
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