HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Randomized, controlled trial of qigong for treatment of prehypertension and mild essential hypertension.

AbstractCONTEXT:
Hypertension treatments include sodium restriction, pharmacological management, and lifestyle modifications. Although many cases of hypertension can be controlled by medication, individuals may experience side effects or incur out-of-pocket expenses, and some may not comply with the treatment regimen. Although some previous studies have shown a favorable effect for qigong on hypertension, well-designed, rigorous trials evaluating the effect of qigong on hypertension are scarce.
OBJECTIVE:
This study aimed to evaluate the effect of qigong on prehypertension and mild hypertension and to calculate a sample size for a subsequent randomized, clinical trial (RCT).
DESIGN:
Participants were randomized to a qigong group or an untreated control group.
SETTING:
This study was conducted at the Oriental Medical Center of Dongeui University, in the Republic of Korea.
PARTICIPANTS:
Participants were individuals between the ages of 19 and 65 y with systolic blood pressure (SBP) between 120 and 159 mm Hg and/or diastolic blood pressure (DBP) between 80 and 99 mm Hg.
INTERVENTION:
The qigong group attended qigong classes 3 ×/wk and performed qigong at home at least 2 ×/wk. Participants in the control group did not receive any intervention for hypertension.
OUTCOME MEASURES:
Outcome measures for this study were (1) changes in blood pressure (BP); (2) quality of life (QOL) using 2 surveys: the Medical Outcomes Study (MOS) 36-item short form (SF-36) (Korean version) and the Measure Yourself Medical Outcome Profile 2 (MYMOP2); and (3) hormone levels.
RESULTS:
Of 40 participants, 19 were randomly assigned to the qigong group, and 21 were assigned to the control group. After 8 wk, significant differences were observed between the qigong and the control groups regarding changes in SBP (P = .0064) and DBP (P = .0003). Among the categories of the MYMOP2 questionnaire, only wellbeing was significantly different between the 2 groups (P = .0322). The qigong group showed a significantly greater improvement in the physical component score of the SF-36 compared with the control group (P = .0373). Regarding changes in hormone levels, there was no significant difference between the qigong and the control groups. This pilot study demonstrates that regarding sample size, a RCT evaluating the effect of qigong on hypertension should include 22 participants based on DBP and 285 participants based on SBP in each group, thus allowing for a loss to follow-up rate of 20%.
CONCLUSION:
The results indicate that qigong may be an effective intervention in reducing BP in prehypertension and mild hypertension. Further studies should include an appropriate sample size and methodology to determine the mechanism of qigong on BP.
AuthorsJi-Eun Park, Sanghoon Hong, Minhee Lee, Taeseob Park, Kyungwon Kang, Heejung Jung, Kyung-Min Shin, Yan Liu, Misuk Shin, Sun-Mi Choi
JournalAlternative therapies in health and medicine (Altern Ther Health Med) 2014 Jul-Aug Vol. 20 Issue 4 Pg. 21-30 ISSN: 1078-6791 [Print] United States
PMID25141360 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Cholesterol
  • Hydrocortisone
Topics
  • Adult
  • Aged
  • Blood Pressure (physiology)
  • Cholesterol (blood)
  • Essential Hypertension
  • Health Surveys
  • Humans
  • Hydrocortisone (blood)
  • Hypertension (blood, physiopathology, therapy)
  • Middle Aged
  • Prehypertension (blood, physiopathology, therapy)
  • Qigong
  • Quality of Life
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: