Olanzapine-induced restless leg syndrome: a case report and review of literature.

Abstract

Restless leg syndrome (RLS) is a common disorder causing sleep impairment. Antipsychotics particularly belonging to the first generation are a common cause of RLS. Whereas, RLS induced by olanzapine is rare, there are only a few cases reported earlier. We report a 38-year-old lady suffering from persistent delusional disorder who was prescribed olanzapine. She developed RLS after initiation of olanzapine which improved when switched over to risperidone. This report will caution clinicians about this side effect of a very commonly prescribed antipsychotic drug.

• Authors: Aniruddha Basu, Savita Kundu, Hitesh Khurana
• Journal: Indian journal of pharmacology (Indian J Pharmacol) 2014 Jul-Aug Vol. 46 Issue 4 Pg. 450-2 ISSN: 1998-3751 [Electronic] India
• PMID: 25097291 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antipsychotic Agents
• Benzodiazepines
• Olanzapine

Topics

• Adult
• Antipsychotic Agents (administration & dosage, adverse effects, therapeutic use)
• Benzodiazepines (administration & dosage, adverse effects, therapeutic use)
• Delusions (drug therapy, psychology)
• Humans
• Olanzapine
• Restless Legs Syndrome (chemically induced, diagnosis, drug therapy)
• Severity of Illness Index