Topical tacrolimus in the management of oral lichen planus: literature review.

Abstract

Tacrolimus is an immunosuppressive property approved for the treatment of atopic dermatitis. Studies have shown that topical tacrolimus is effective for a broad spectrum of mucocutaneous diseases, including oral lichen planus. The objective of this article is to review the pharmacology of tacrolimus, its usage in oral lichen planus, adverse effects and advantages of tacrolimus over other conventional drugs, thus making it a popular and alternative drug for the treatment of lichen planus.

• Authors: P S Shilpa, Rachna Kaul, Suraksha Bhat, C J Sanjay, Nishat Sultana
• Journal: Journal of the California Dental Association (J Calif Dent Assoc) Vol. 42 Issue 3 Pg. 165-70 (Mar 2014) ISSN: 1043-2256 [Print] United States
• PMID: 25080722 (Publication Type: Journal Article, Review)

Chemical References

• Carcinogens
• Immunosuppressive Agents
• Tacrolimus

Topics

• Administration, Topical
• Carcinogens
• Humans
• Immunosuppressive Agents (administration & dosage, adverse effects)
• Lichen Planus, Oral (drug therapy)
• Tacrolimus (administration & dosage, adverse effects)