Clonazepam in juvenile myoclonic epilepsy.

Abstract

We studied the efficacy of clonazepam (CZP) in control of juvenile myoclonic epilepsy (JME) in 17 patients. CZP was very effective in controlling myoclonic jerks in all patients but did not suppress generalized tonic-clonic seizures (GTCS). A disadvantage occurs because the patient is deprived of the warning jerks which presage the onset of GTCS. The circadian rhythm of the GTCS was also changed in two patients.

• Authors: T Obeid, C P Panayiotopoulos
• Journal: Epilepsia (Epilepsia) 1989 Sep-Oct Vol. 30 Issue 5 Pg. 603-6 ISSN: 0013-9580 [Print] United States
• PMID: 2507306 (Publication Type: Journal Article)

Chemical References

• Drug Combinations
• Carbamazepine
• Clonazepam
• Valproic Acid
• Phenytoin

Topics

• Adolescent
• Adult
• Carbamazepine (therapeutic use)
• Circadian Rhythm (drug effects)
• Clonazepam (therapeutic use)
• Drug Combinations
• Epilepsies, Myoclonic (drug therapy)
• Female
• Follow-Up Studies
• Humans
• Male
• Myoclonus (drug therapy)
• Phenytoin (therapeutic use)
• Prospective Studies
• Valproic Acid (therapeutic use)