[Flecainide acetate in the acute and medium-term prophylactic treatment of 2 cases of ectopic atrial tachycardia].

Abstract

The aim of this study is to evaluate the efficacy of flecainide acetate, which was administered intravenously, to induce cardioversion in 2 female patients of 48 and 76 years, with ectopic atrial tachycardia. Besides the clinical examination, ECG monitoring by radiotelemetry, chest x-ray, echocardiographic examination, thyroid tests and other routine hematochemical tests, we carried out an endocavitary electrophysiologic study, followed by pharmacologic tests in series: propranolol (5 mg/5 min iv), verapamil (5 mg/5 min iv) and flecainide (1.5 mg/kg/15 min iv). We confirmed the presumptive diagnosis of ectopic atrial tachycardia and that, among all the drugs tested, flecainide acetate was the only one restoring the sinus rhythm. In a medium-term follow-up, during which the patients were treated with flecainide, 100 mg twice-a-day, we didn't notice relapse of the tachycardia and the patients tolerated the drug well.

• Authors: S Tognarini, E Pardini
• Journal: Cardiologia (Rome, Italy) (Cardiologia) Vol. 34 Issue 6 Pg. 567-70 (Jun 1989) ISSN: 0393-1978 [Print] Italy
• Vernacular Title: Trattamento acuto e profilassi a medio termine con flecainide acetato in 2 casi di tachicardia atriale ectopica.
• PMID: 2507142 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Flecainide

Topics

• Aged
• Echocardiography
• Electrocardiography
• Female
• Flecainide (therapeutic use)
• Humans
• Middle Aged
• Tachycardia, Ectopic Atrial (drug therapy, physiopathology)
• Tachycardia, Supraventricular