Effects of pre-operative submucosal dexamethasone injection on the postoperative swelling and trismus following surgical extraction of mandibular third molar.

Abstract

OBJECTIVE:

To determine the effects of pre-operative submucosal dexamethasone injection on postoperative swelling and trismus following surgical extraction of mandibular third molar.

STUDY DESIGN:

Randomized controlled trial.

PLACE AND DURATION OF STUDY:

Department of Oral and Maxillofacial Surgery, Armed Forces Institute of Dentistry (AFID), Rawalpindi, from October 2009 to March 2010.

METHODOLOGY:

A total of 100 patients aged 18 - 40 years with good periodontal health and mesioangular impaction were divided in two treatment groups (50 in each group). Group-A received prophylactic 4 mg submucosal dexamethasone intraoral injection and Group-B acted as control group. Facial swelling and trismus were assessed at baseline, 2nd and 7th postoperative days. Data was analyzed using SPSS-10.

RESULTS:

There were 35 (70%) males and 15 (30%) females in group-A and 34 (68%) males and 16 (32%) females in group-B. Surgical time ranged from 30 - 50 minutes (mean = 40.62 ± 4.886 minutes) for group-A and 33 - 50 minutes (mean = 42.12 ± 4.543 minutes) for group-B. Administration of dexamethasone had statistically significant effect in reduction of swelling and trismus on second postoperative day (p < 0.05) in group-A.

CONCLUSION:

Pre-operative 4 mg submucosal dexamethasone injection was significantly effective in reduction of postoperative swelling and trismus.

• Authors: Afeefa Ehsan, Syed Gulzar Ali Bukhari, Ashar, Arslan Manzoor, Muhammad Junaid
• Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP (J Coll Physicians Surg Pak) Vol. 24 Issue 7 Pg. 489-92 (Jul 2014) ISSN: 1681-7168 [Electronic] Pakistan
• PMID: 25052972 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Anti-Inflammatory Agents
• Glucocorticoids
• Dexamethasone

Topics

• Adolescent
• Adult
• Anti-Inflammatory Agents (administration & dosage, therapeutic use)
• Dexamethasone (administration & dosage)
• Edema (prevention & control)
• Female
• Glucocorticoids (administration & dosage, therapeutic use)
• Humans
• Injections
• Male
• Molar, Third (surgery)
• Pain Measurement
• Pain Threshold (drug effects)
• Pain, Postoperative (drug therapy, prevention & control)
• Postoperative Complications (prevention & control)
• Postoperative Period
• Prospective Studies
• Tooth Extraction
• Treatment Outcome
• Trismus (prevention & control)