HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Jatropha seed oils extracted by different methods and their effect on killing cercaria of Schistosoma japonicum].

AbstractOBJECTIVE:
To evaluate the effect of Jatropha seed oils extracted by different methods on killing cercaria of Schistosomajaponicum so as to screen the optimum process and formulations.
METHODS:
The cercaria directly contacting tests with Jatropha seed oils extracted by 6 different extraction processes were carried out, and the mouse immediate contacting cercaria infection trials with different formulations of Jatropha seed oil and various additives were performed.
RESULTS:
With 95% ethanol, the ratio of material to liquid being 1:8, and 2 h extraction, the oil extraction rate was 30.7%. The cercaria directly contacting tests showed that 6 kinds of Jatropha seed oil killed all cercaria within 30 min. In the mouse immediate contacting cercaria infection trials, the worm declined rate of Jatropha seed oil liquid was 70.97%, and the worm declined rate of the sample added with benzyl benzoate was 58.87%, and the worm declined rate of the sample added with laurocapram was 77.42%. The worm declined rate of the samples added with benzyl benzoate, dibutyl phthalate and laurocapram was 100%.
CONCLUSION:
The process with 95% ethanol, the ratio of material to liquid being 1:8, and 2 h extraction is the optimum, and the Jatropha seed oil has a good killing schistosome cercaria effect.
AuthorsPing Yi, Qu-zhi Yu, Wen Qu, Ying Xia, Wen-hua Cheng, Shuang Li, Qin-qi Liu, Yao Tong, Li-jun Tang
JournalZhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control (Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi) Vol. 26 Issue 2 Pg. 187-8, 191 (Apr 2014) ISSN: 1005-6661 [Print] China
PMID25051835 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Plant Oils
Topics
  • Animals
  • Cercaria (drug effects)
  • Chemical Fractionation (methods)
  • Female
  • Jatropha (chemistry)
  • Male
  • Mice
  • Plant Oils (isolation & purification, pharmacology)
  • Schistosoma japonicum (drug effects)
  • Seeds (chemistry)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: