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Pre-operative ⁶⁸Ga-DOTANOC somatostatin receptor PET/CT imaging demonstrating multiple synchronous lesions in a patient with head and neck paraganglioma.

Abstract
Paragangliomas, or glomus tumors, are neoplasms arising from extra-adrenal chromaffin tissue. They frequently cause symptoms by over-production of catecholamines with known predilection to multicentricity. We describe the case of a patient with bilateral carotid body tumor who underwent a preoperative ⁶⁸Gallium labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide (⁶⁸Ga-DOTANOC) positron emission tomography/computed tomography (PET/CT) imaging for staging. This is a unique case in which multiple paraganglioma and pheochromocytoma were demonstrated in a single patient using ⁶⁸Ga-DOTANOC PET/CT.
AuthorsN Naswa, S Karunanithi, P Sharma, R Soundararajan, C Bal, R Kumar
JournalRevista espanola de medicina nuclear e imagen molecular (Rev Esp Med Nucl Imagen Mol) 2014 Nov-Dec Vol. 33 Issue 6 Pg. 374-7 ISSN: 2253-8070 [Electronic] Spain
PMID25043773 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2013 Elsevier España, S.L.U. and SEMNIM. All rights reserved.
Chemical References
  • 68Ga-DOTANOC
  • Neoplasm Proteins
  • Organometallic Compounds
  • Radiopharmaceuticals
  • Receptors, Somatostatin
Topics
  • Abdominal Neoplasms (chemistry, diagnostic imaging)
  • Adrenal Gland Neoplasms (chemistry, diagnostic imaging)
  • Carotid Body Tumor (chemistry, diagnostic imaging)
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Mediastinal Neoplasms (chemistry, diagnostic imaging)
  • Middle Aged
  • Multimodal Imaging
  • Neoplasm Proteins (analysis)
  • Neoplasms, Multiple Primary (chemistry, diagnostic imaging)
  • Organometallic Compounds (analysis)
  • Paraganglioma (chemistry, diagnostic imaging)
  • Pheochromocytoma (chemistry, diagnostic imaging)
  • Positron Emission Tomography Computed Tomography
  • Preoperative Care
  • Radiopharmaceuticals (analysis)
  • Receptors, Somatostatin (analysis)
  • Sensitivity and Specificity
  • Whole Body Imaging

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