Abstract | BACKGROUND: It is reported that patients on oral isotretinoin have greater risk of developing scars and delayed wound healing with invasive procedures. It is recommended that these procedures be resumed 6-12 months after the last dose of oral isotretinoin. AIM: METHODS: A comparative, retrospective study of 110 patients was done. Fifty-five patients with either acne scars or hirsutism who underwent procedures while on oral isotretinoin, and 55 patients who were not on oral isotretinoin were selected and grouped into A and B respectively. Group A patients were on 0.5 mg/kg/day isotretinoin orally through the entire procedure duration, while group B patients received topical medications alone. The subjects from both groups underwent invasive acne scar treatment and laser hair removal. Clinical and photographic assessment was done at baseline followed by four sessions with an interval of six weeks between each. RESULTS: CONCLUSION:
Isotretinoin does not appear to delay wound healing, and hence invasive procedures can be considered on patients on oral isotretinoin without any compromise on the outcome.
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Authors | Byalakere Shivanna Chandrashekar, Danda Venkatesh Varsha, Vani Vasanth, Puttarangappa Jagadish, Chandraiah Madura, Maragowdanahalli Lingegowda Rajashekar |
Journal | International journal of dermatology
(Int J Dermatol)
Vol. 53
Issue 10
Pg. 1281-5
(Oct 2014)
ISSN: 1365-4632 [Electronic] England |
PMID | 25039864
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Copyright | © 2014 The International Society of Dermatology. |
Chemical References |
- Dermatologic Agents
- Isotretinoin
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Topics |
- Acne Vulgaris
(complications, drug therapy)
- Administration, Oral
- Adolescent
- Adult
- Cicatrix
(etiology, surgery)
- Dermatologic Agents
(administration & dosage)
- Female
- Hair Removal
(methods)
- Humans
- Isotretinoin
(administration & dosage)
- Lasers
- Male
- Middle Aged
- Retrospective Studies
- Young Adult
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