Navigation lymphatic supermicrosurgery for iatrogenic lymphorrhea: supermicrosurgical lymphaticolymphatic anastomosis and lymphaticovenular anastomosis under indocyanine green lymphography navigation.

Abstract

BACKGROUND:

Lymphorrhea can occur after surgical intervention to the lymphatic system. Most cases with lymphorrhea can be treated conservatively, but some cases are refractory to conservative treatments and require further surgical treatments.

METHODS:

Eight patients developed inguinal lymphorrhea after surgical intervention in the groin region. Navigation lymphatic supermicrosurgery (NLS) was performed for the treatment of iatrogenic lymphorrhea refractory to conservative treatments. Lymphatic vessels ruptured in a lymphorrhea lesion were identified under intraoperative indocyanine green (ICG) lymphography navigation and were anastomosed to a recipient vessel; an intact lymphatic vessel or a vein was selected as a recipient. Feasibility and efficacy of the method were evaluated.

RESULTS:

Among eight inguinal lymphorrhea patients, four patients with refractory lymphorrhea underwent NLS under local anesthesia. In all cases, a lymphatic vessel that caused an intractable lymphorrhea was successfully anastomosed to a recipient vessel (to an intact lymphatic vessel in one case, and to a venule in three cases), and the lymphorrhea was completely cured without lymphorrhea recurrence or lymphedema development. Treatment duration in NLS was significantly shorter than that in conservative treatments (5.0 ± 2.4 vs. 30.0 ± 8.1 days, P = 0.006).

CONCLUSIONS:

Intraoperative ICG lymphography helps a surgeon to find lymphatic vessels in and near a lymphorrhea lesion, which allows secure and easier treatment for an intractable lymphorrhea with preservation of lymph drainage function.

• Authors: Takumi Yamamoto, Hidehiko Yoshimatsu, Isao Koshima
• Journal: Journal of plastic, reconstructive & aesthetic surgery : JPRAS (J Plast Reconstr Aesthet Surg) Vol. 67 Issue 11 Pg. 1573-9 (Nov 2014) ISSN: 1878-0539 [Electronic] Netherlands
• PMID: 25023202 (Publication Type: Journal Article)
• Copyright: Copyright © 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Chemical References

• Coloring Agents
• Indocyanine Green

Topics

• Adult
• Aged
• Anastomosis, Surgical
• Biopsy (adverse effects)
• Coloring Agents
• Female
• Groin (surgery)
• Humans
• Iatrogenic Disease
• Indocyanine Green
• Lymphatic Vessels (diagnostic imaging, injuries, surgery)
• Lymphography (methods)
• Male
• Microscopy
• Microsurgery (methods)
• Middle Aged
• Surgical Flaps (adverse effects)
• Treatment Outcome