[Methemoglobinemia after accidental Nestosyl ingestion].

Abstract

Nestosyl is usually used for dental pain in children. We report a methemoglobinemia after accidental ingestion of 10 ml in a 2 year-old girl. Cyanosis was cleared and O2 saturation and PaO2 were normalized 15 mn after methylene blue (1 mg/kg) administered intravenously. Nestosyl contains butoform, benzocaine, resorcine and 8-hydroxyquinoleine: the 3 latest can induce methemoglobinemia. The benefit of the drug is not demonstrated and this potentially severe side effect justifies its delivery only after medical prescription and information about its dangers.

• Authors: E Autret, E Forveille-Fournier, S Marchand, A P Jonville, N Ramponi
• Journal: Archives francaises de pediatrie (Arch Fr Pediatr) Vol. 46 Issue 4 Pg. 271-2 (Apr 1989) ISSN: 0003-9764 [Print] France
• Vernacular Title: Méthémoglobinémie après ingestion accidentelle de Nestosyl.
• PMID: 2502102 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anesthetics, Local
• Drug Combinations
• Hydroxyquinolines
• Oxyquinoline
• Nestosyl ointment

Topics

• Anesthetics, Local (poisoning)
• Cyanosis (etiology)
• Drug Combinations (poisoning)
• Female
• Humans
• Hydroxyquinolines (poisoning)
• Infant
• Methemoglobinemia (chemically induced, complications)
• Oxyquinoline (poisoning)