Abstract | BACKGROUND: METHODS: In a case series, 18 eyes of 18 patients with diagnosis of indirect TON with duration of less than 2 weeks underwent 20,000 IU intravenous EPO injections daily for 3 days. Best corrected visual acuity (BCVA) and color vision were checked by Ishihara test before, 1, and 3 months after injections. BCVA and color vision were compared before, 1, and 3 months after injections. RESULTS: The mean BCVA improved from a baseline of 2.21 ± 0.97 to 1.48 ± 1.29 and 1.31 ± 1.27 log MAR at months 1 and 3, respectively. The differences were statistically significant (P = 0.001, P < 0.001). Color vision was changed from a baseline 2.24 ± 4.29 to 2.94 ± 4.64 and 3.41 ± 5.09 plates at months 1 and 3, respectively. We observed some qualitative improvement that was, however, statistically insignificant at the time of evaluation. (P = 0.063, P = 0.068). CONCLUSION: This case series showed noticeable effect of EPO on improvement of visual function in patients with recent indirect TON.
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Authors | Morteza Entezari, Manuchehr Esmaeili, Mehdi Yaseri |
Journal | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
(Graefes Arch Clin Exp Ophthalmol)
Vol. 252
Issue 8
Pg. 1309-13
(Aug 2014)
ISSN: 1435-702X [Electronic] Germany |
PMID | 24986593
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Child
- Child, Preschool
- Color Vision
(drug effects, physiology)
- Erythropoietin
(administration & dosage)
- Female
- Humans
- Infusions, Intravenous
- Male
- Middle Aged
- Optic Nerve Injuries
(drug therapy, physiopathology)
- Pilot Projects
- Visual Acuity
(drug effects, physiology)
- Young Adult
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