Elastosis perforans serpiginosa: a case successfully treated with intralesional steroids and topical allium cepa-allantoin-pentaglycan gel.

Abstract

Elastosis perforans serpiginosa is a rare skin disease in which abnormal elastic fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis through the epidermis. Three clinical variants of EPS can be detected: idiopathic, reactive, and drug-induced. Clinically it consists of small horny or umbilicated papules arranged in a linear, arciform, circular, or serpiginous pattern. It usually occurs in young adults and shows a predilection for the head and neck. The lesions are generally asymptomatic or slightly itching. Several treatments have been reported with poor long-term success; these include intralesional and topical corticosteroids, tazarotene, imiquimod, and cryotherapy. We report a case of 40-year-old black woman affected by elastosis perforans serpiginosa that was referred to our department and treated with intralesional injections of triamcinolone acetonide and topical application of allium cepa-allantoin-pentaglycan gel.

• Authors: Anna Campanati, Emanuela Martina, Katia Giuliodori, Giulia Ganzetti, Barbara Marconi, Irene Conta, Mirella Giangiacomi, Annamaria Offidani
• Journal: Acta dermatovenerologica Alpina, Pannonica, et Adriatica (Acta Dermatovenerol Alp Pannonica Adriat) Vol. 23 Issue 2 Pg. 39-41 ( 2014) ISSN: 1581-2979 [Electronic] Slovenia
• PMID: 24964949 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Plant Extracts
• Polysaccharides
• Allantoin
• Triamcinolone Acetonide

Topics

• Administration, Topical
• Adult
• Allantoin (administration & dosage)
• Female
• Glucocorticoids (administration & dosage)
• Humans
• Injections, Intralesional
• Onions
• Plant Extracts (administration & dosage)
• Polysaccharides (administration & dosage)
• Remission Induction
• Skin Diseases (drug therapy)
• Triamcinolone Acetonide (administration & dosage)