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Invasive group A streptococcal infection in the Northern Territory, Australia: case report and review of the literature.

Abstract
The increasing incidence of invasive group A streptococcus has been well documented in the temperate climates of North America, Europe and the United Kingdom. Studies also suggest that there are high rates of invasive group A streptococcus infection within the indigenous population of Northern Australia. This review article presents the case of infant Aboriginal twins with invasive group A streptococcal infection complicated by streptococcal toxic shock syndrome, highlighting both the severity and high transmissibility of invasive group A streptococcal disease. We review the epidemiology of group A streptococcal infection and suggest a potential role for chemoprophylaxis of household contacts to reduce the burden of disease within the indigenous population of Northern Australia.
AuthorsBianca Middleton, Peter Morris, Jonathan Carapetis
JournalJournal of paediatrics and child health (J Paediatr Child Health) Vol. 50 Issue 11 Pg. 869-73 (Nov 2014) ISSN: 1440-1754 [Electronic] Australia
PMID24957474 (Publication Type: Case Reports, Journal Article, Review)
Copyright© 2014 The Authors. Journal of Paediatrics and Child Health © 2014 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
Chemical References
  • Anti-Bacterial Agents
Topics
  • Anti-Bacterial Agents (administration & dosage)
  • Bacteremia (diagnosis, therapy)
  • Combined Modality Therapy
  • Debridement (methods)
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intensive Care Units, Neonatal
  • Northern Territory
  • Risk Assessment
  • Streptococcal Infections (diagnosis, therapy)
  • Streptococcus pyogenes (isolation & purification)
  • Treatment Outcome
  • Twins

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