Abstract |
A prospective double-blind placebo-controlled trial conducted during a 6-month period showed that lithium carbonate was no better than placebo in producing total abstinence in patients with alcoholism, regardless of whether they were depressed. A high dropout rate, the effect of compliance, and difficulties in measuring improvement in these patients impose some limitations in interpreting the results of this study.
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Authors | J R de la Fuente, R M Morse, R G Niven, D M Ilstrup |
Journal | Mayo Clinic proceedings
(Mayo Clin Proc)
Vol. 64
Issue 2
Pg. 177-80
(Feb 1989)
ISSN: 0025-6196 [Print] England |
PMID | 2493536
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Lithium Carbonate
- Lithium
|
Topics |
- Adult
- Aged
- Alcoholism
(drug therapy)
- Double-Blind Method
- Drug Evaluation
- Female
- Humans
- Lithium
(therapeutic use)
- Lithium Carbonate
- Male
- Middle Aged
- Patient Compliance
- Prospective Studies
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