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Low-dose imipramine for treatment of panic disorder during pregnancy: a retrospective chart review.

Abstract
Although imipramine is one of the antidepressants that could be effective in the treatment of panic disorder, data on its usage for this diagnosis in the pregnancy period are limited. This report presents the results of 16 pregnant women with panic disorder without comorbid diagnosis who underwent low-dose imipramine (10-40 mg/d) treatment. According to the Clinical Global Impression-Improvement Scale, 12 (75%) of 16 women responded to the treatment. The results suggest that low-dose imipramine may be useful for the treatment of panic disorder during pregnancy.
AuthorsFaruk Uguz, Mine Sahingoz, Buket Gungor, Rustem Askin
JournalJournal of clinical psychopharmacology (J Clin Psychopharmacol) Vol. 34 Issue 4 Pg. 513-5 (Aug 2014) ISSN: 1533-712X [Electronic] United States
PMID24875076 (Publication Type: Journal Article)
Chemical References
  • Antidepressive Agents, Tricyclic
  • Imipramine
Topics
  • Adult
  • Antidepressive Agents, Tricyclic (administration & dosage)
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Imipramine (administration & dosage)
  • Infant, Newborn
  • Panic Disorder (diagnosis, drug therapy, epidemiology)
  • Pregnancy
  • Pregnancy Complications (diagnosis, drug therapy, epidemiology)
  • Retrospective Studies
  • Treatment Outcome
  • Turkey (epidemiology)
  • Young Adult

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