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All children with malignant rhabdoid tumors should be treated initially with intensive chemotherapy.

Abstract
Malignant rhabdoid tumors (MRT) of soft tissues are aggressive tumors, which can be detected in almost any part of the body. MRT are rare, and very few cases have been reported in the literature. Prognosis of these tumors is extremely poor despite intensive therapy. Some risk factors such as young age or disseminated disease are associated with an aggressive and almost always lethal clinical course. Some clinicians even recommend initial palliative care due to this outcome. We report a case of metastatic MRT in a 6-month-old child with excellent initial response to chemotherapy.
AuthorsC Hernández-Marqués, A Lassaletta, M Cormenzana, E García-Esparza, L Madero-López
JournalPediatric hematology and oncology (Pediatr Hematol Oncol) Vol. 32 Issue 3 Pg. 193-8 (Apr 2015) ISSN: 1521-0669 [Electronic] England
PMID24852450 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Dactinomycin
  • Vincristine
  • Etoposide
  • Doxorubicin
  • Cyclophosphamide
  • Cisplatin
  • Ifosfamide
Topics
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Cisplatin (therapeutic use)
  • Cyclophosphamide (therapeutic use)
  • Dactinomycin (therapeutic use)
  • Doxorubicin (therapeutic use)
  • Etoposide (therapeutic use)
  • Humans
  • Ifosfamide (therapeutic use)
  • Infant
  • Male
  • Mediastinal Neoplasms (diagnostic imaging, drug therapy, pathology)
  • Rhabdoid Tumor (diagnostic imaging, drug therapy, pathology)
  • Tomography, X-Ray Computed
  • Vincristine (therapeutic use)

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