Skin-sparing mastectomy flap ischemia salvage using urgent hyperbaric chamber oxygen therapy: a case report.

Since its introduction in 1991, skin-sparing mastectomy has emerged as an acceptable surgical technique in the management of breast cancer patients, providing optimal oncological safety and efficacy with favorable aesthetic results. Rates of native skin flap ischemia and necrosis after skin-sparing mastectomy are 2%-30% and result in a decreased aesthetic outcome and delay of necessary adjuvant treatment. Hyperbaric oxygen therapy has been advocated for the management of various compromised flaps, and when instituted immediately postoperatively, may prevent progression of ischemia into necrosis. We report the case of a 41-year-old female who developed skin flap ischemia after undergoing skin-sparing mastectomy and was immediately treated with hyperbaric oxygen. The patient received a total of five hyperbaric oxygen therapy sessions, achieving full resolution of the ischemia without any complications. Further research is essential to determine the role of hyperbaric oxygen therapy in managing skin flap ischemia post skin-sparing mastectomy. Until such studies exist, hyperbaric oxygen therapy may be considered a preferred option in the management of native skin flap ischemia after skin-sparing mastectomy.
AuthorsRafi Fredman, Itay Wise, Tali Friedman, Lior Heller, Tami Karni
JournalUndersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc (Undersea Hyperb Med) 2014 Mar-Apr Vol. 41 Issue 2 Pg. 145-7 ISSN: 1066-2936 [Print] United States
PMID24851552 (Publication Type: Case Reports, Journal Article)
  • Adenocarcinoma, Mucinous (therapy)
  • Adult
  • Breast Neoplasms (therapy)
  • Carcinoma, Ductal, Breast (therapy)
  • Female
  • Humans
  • Hyperbaric Oxygenation
  • Ischemia (therapy)
  • Mastectomy (methods)
  • Necrosis (prevention & control)
  • Organ Sparing Treatments (methods)
  • Salvage Therapy (methods)
  • Surgical Flaps (blood supply, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password:
Type Validation Code Shown: