Abstract | OBJECTIVE: The aims of the study were to clarify the occurrence of disturbance in surgical wound healing (DSWH) after surgery of zygomatic complex (ZC) fractures and to determine whether perioperatively applied dexamethasone increases the risk for DSWH. STUDY DESIGN: Of 64 patients who were included in a single-blind prospective trial, 33 perioperatively received a total dose of 10 mg or 30 mg of dexamethasone. The remaining 31 patients served as controls. RESULTS: DSWH occurred in 9 patients (14.1%). Occurrence of DSWH was 24.4% in patients who received dexamethasone and 3.2% in controls. The association between DSWH and dexamethasone was significant (P = .016). Intraoral approach also was associated with DSWH significantly (P = .042). No association emerged between DSWH and age, gender, time span from accident to surgery, or duration of surgery. CONCLUSIONS: DSWH occurred significantly more frequently in patients who received perioperative dexamethasone. Because of increased risk of DSWH, perioperative dexamethasone cannot be recommended in open reduction and fixation of ZC fractures.
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Authors | Johanna Snäll, Eeva Kormi, Anna-Maria Koivusalo, Christian Lindqvist, Anna Liisa Suominen, Jyrki Törnwall, Hanna Thorén |
Journal | Oral surgery, oral medicine, oral pathology and oral radiology
(Oral Surg Oral Med Oral Pathol Oral Radiol)
Vol. 117
Issue 6
Pg. 685-9
(Jun 2014)
ISSN: 2212-4411 [Electronic] United States |
PMID | 24842445
(Publication Type: Journal Article, Randomized Controlled Trial)
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Copyright | Copyright © 2014 Elsevier Inc. All rights reserved. |
Chemical References |
- Glucocorticoids
- Dexamethasone
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Dexamethasone
(therapeutic use)
- Female
- Fracture Fixation, Internal
(methods)
- Glucocorticoids
(therapeutic use)
- Humans
- Male
- Middle Aged
- Prospective Studies
- Single-Blind Method
- Treatment Outcome
- Wound Healing
(drug effects)
- Zygomatic Fractures
(surgery)
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