Myoglobinuria masquerading as acute rejection in a renal allograft recipient with recurrent post transplant diabetic nephropathy.

Abstract

Rhabdomyolysis contributes to 7-10% of total AKI cases. Myoglobinuria as a cause of acute renal allograft dysfunction is extremely uncommon. Renal allograft recipient on cyclosporine or tacrolimus can develop myoglobinuria in presence of other precipitating factors. Present case describes an interesting report of myoglobinuria in a patient with post transplant diabetic nephropathy mimicking acute graft rejection. Clinically myoglobinuria presenting as renal allograft dysfunction is diagnosis of exclusion and renal biopsy is extremely important in making a correct diagnosis and planning optimal management in such cases.

• Authors: Pallav Gupta, Amit Sharma, Dinesh Khullar
• Journal: Renal failure (Ren Fail) Vol. 36 Issue 7 Pg. 1133-5 (Aug 2014) ISSN: 1525-6049 [Electronic] England
• PMID: 24826952 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Allografts
• Diabetic Nephropathies (complications, pathology)
• Diagnosis, Differential
• Graft Rejection (diagnosis)
• Humans
• Kidney (pathology)
• Kidney Transplantation
• Male
• Myoglobinuria (diagnosis, etiology)
• Postoperative Complications (diagnosis, etiology, pathology)
• Rhabdomyolysis (complications)