[De novo diabetic glomerulosclerosis in kidney transplants].

Abstract

Report on 3 cases who had been non-diabetics at the time of cadaver kidney transplantation. After that within 1-5 years diabetes mellitus developed. The patients died 13-14 years after transplantation (9-12 years of diabetes duration). Autopsy revealed typical nodular glomerulosclerosis including diffuse mesangial widening, glomerular aneurysms, exudative lesions, capsular drops, arteriolosclerosis, and in 2 cases with hyalinosis of the vas efferens; moreover, chronic transplant glomerulopathy was found in all cases. Steroid therapy seemed to be responsible for the diabetic state, in 2 cases apparently in combination with disposition.

• Authors: G Ditscherlein, D Scholz, W Blank, P Reinke, R Meyer, T Decker
• Journal: Verhandlungen der Deutschen Gesellschaft fur Pathologie (Verh Dtsch Ges Pathol) Vol. 73 Pg. 238-41 ( 1989) ISSN: 0070-4113 [Print] Germany
• Vernacular Title: Diabetische Glomerulosklerose de novo in Neirentransplantaten.
• PMID: 2482608 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Diabetic Nephropathies (etiology, pathology)
• Humans
• Kidney Transplantation (pathology)