HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Management of stomal varices with transvenous obliteration utilizing sodium tetradecyl sulfate foam sclerosis.

Abstract
The management of parastomal varices is not established. Transjugular intrahepatic portosystemic shunt (TIPS) creation is the most commonly described treatment; however, the rebleed rate after TIPS is 21-37%. The purpose of the study is to determine the effectiveness of transvenous obliteration using sodium tetradecyl sulfate (STS) and to describe a new simplified technique in obliterating these varices. Four patients are presented who underwent transvenous obliteration using STS. One was obliterated using balloon occlusion from the systemic veins, the second was obliterated without balloon from a transhepatic antegrade approach, and the last two patients were obliterated using the direct antegrade technique. This simplified technique requires only a micropuncture kit (not requiring balloons or coils) and ultrasound transducer compression of the systemic draining veins, relying on high portal pressure to keep the sclerosant confined to the varices. The sclerosant is essentially trapped between the portal pressure and the ultrasound-transducer compression (10-15 min). Technical success was achieved in all four patients without procedural or postprocedural complications and no rebleeding for a mean follow-up of 17 (range 2-33) months. Transvenous obliteration of parastomal varices utilizing STS as a sclerosant is safe and effective. The newly described technique is simple, feasible, and requires minimal equipment (no balloons or coils or catheters).
AuthorsWael E A Saad, Sandra Schwaner, Allison Lippert, Saher S Sabri, Abdullah Al-Osaimi, Alan H Matsumoto, John F Angle, Stephen Caldwell
JournalCardiovascular and interventional radiology (Cardiovasc Intervent Radiol) Vol. 37 Issue 6 Pg. 1625-30 (Dec 2014) ISSN: 1432-086X [Electronic] United States
PMID24798128 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Sclerosing Solutions
  • Sodium Tetradecyl Sulfate
Topics
  • Adult
  • Aged, 80 and over
  • Collateral Circulation
  • Esophageal and Gastric Varices (therapy)
  • Female
  • Humans
  • Ileostomy
  • Male
  • Middle Aged
  • Sclerosing Solutions (therapeutic use)
  • Sclerotherapy (methods)
  • Sodium Tetradecyl Sulfate (therapeutic use)
  • Ultrasonography, Interventional

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: