[Eye infections caused by Purpureocillium lilacinum: A case report and literature review].

Abstract

BACKGROUND:

Purpureocillium lilacinum eye infections (previously called Paecilomyces lilacinus) make up a significant percentage of the recorded cases of infection by this fungus, and is considered as an emerging pathogen.

AIMS:

To report a case of ocular mycosis in a patient aged 70, with a double corneal transplantation in the right eye, and exhibiting a poor response to antifungal and surgical treatment.

METHODS:

Corneal ring and ocular tissues obtained by surgical procedures were cultured in common mycological media. Molecular identification of the isolated fungus was obtained.

RESULTS:

Colonies of a filamentous fungus were obtained, and according to the macroscopic and microscopic morphology it was identified as P. lilacinum. The identification was confirmed by molecular methods in a reference laboratory.

CONCLUSIONS:

Eye infections due to P. lilacinum are rare but serious diseases that requires rapid diagnostic and therapeutic measures to enable visual function to recover.

• Authors: Ramiro López-Medrano, Alberto Pérez Madera, Carlos Fuster Foz
• Journal: Revista iberoamericana de micologia (Rev Iberoam Micol) 2015 Apr-Jun Vol. 32 Issue 2 Pg. 111-4 ISSN: 2173-9188 [Electronic] Spain
• Vernacular Title: Infecciones oculares por Purpureocillium lilacinum: presentación de un caso y revisión de la literatura.
• PMID: 24793075 (Publication Type: Case Reports, English Abstract, Journal Article, Review)
• Copyright: Copyright © 2013 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

Chemical References

• Anti-Infective Agents
• DNA, Fungal
• DNA, Ribosomal Spacer

Topics

• Aged
• Anti-Infective Agents (therapeutic use)
• Cataract Extraction
• Coinfection
• Corneal Transplantation
• Corneal Ulcer (drug therapy, microbiology, surgery)
• DNA, Fungal (genetics)
• DNA, Ribosomal Spacer (genetics)
• Delftia acidovorans (isolation & purification)
• Eye Evisceration
• Female
• Gram-Negative Bacterial Infections (complications)
• Herpes Zoster Ophthalmicus (complications)
• Humans
• Hypocreales (genetics, isolation & purification, pathogenicity)
• Paecilomyces (genetics, isolation & purification, pathogenicity)
• Reoperation
• Ribotyping
• Surgical Wound Infection (drug therapy, microbiology, surgery)