Land-applied goat manure as a source of human Q-fever in the Netherlands, 2006-2010.

Abstract

Studies have shown a link between Q-fever positive farms (QFPFs) and community cases of human Q-fever. Our study is the first to investigate the potential role of contaminated land-applied manure in human Q-fever, based on a large set of nationwide notification and farm management data. Time between manure application and disease onset in geographically linked notified human cases coincided with the incubation period of Q-fever. Proximity of contaminated land parcels predicted human cases better than proximity of QFPFs (80% vs. 58%, 0-5 km in 2009). Incidence around QFPFs and contaminated land parcels decreased with distance, but not around non-contaminated land parcels. Incidence was higher around contaminated land parcels than non-contaminated land parcels (RR = [10],95%CI = [7], [1]-[14,2]). Our findings deliver evidence that, apart from QFPFs, land-applied contaminated manure may be another source of human Q-fever.

• Authors: Tia Hermans, Leonne Jeurissen, Volker Hackert, Christian Hoebe
• Journal: PloS one (PLoS One) Vol. 9 Issue 5 Pg. e96607 ( 2014) ISSN: 1932-6203 [Electronic] United States
• PMID: 24788538 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Manure

Topics

• Animals
• Animals, Domestic
• Animals, Newborn
• Coxiella burnetii (physiology)
• Goat Diseases (epidemiology, microbiology)
• Goats
• Host-Pathogen Interactions
• Humans
• Incidence
• Manure (microbiology)
• Netherlands (epidemiology)
• Q Fever (epidemiology, microbiology)
• Seasons
• Sheep
• Spatio-Temporal Analysis
• Time Factors
• Zoonoses (epidemiology, microbiology)