Effectiveness of therapeutic selective neck dissection in laryngeal cancer.

Abstract

BACKGROUND:

The aim of this study was to evaluate the effectiveness of selective neck dissection (SND) in patients with laryngeal cancer and clinically positive cervical nodes.

SUBJECTS AND METHODS:

A retrospective review of the clinical records of 58 consecutive untreated patients affected by laryngeal carcinoma and submitted to surgical treatment was performed.

RESULTS:

Twenty-six (44.8%) patients received monolateral neck dissection and 32 (55.2%) bilateral neck dissection. A total of 90 hemineck dissections were performed. Histopathological examination revealed that 25 of the 58 patients had negative nodes (pN0) and 33 had positive nodes (pN+). Extracapsular spread was found in 12 of the 33 pN+ patients. Twenty-eight of the 58 (48.2%) patients were submitted to adjuvant radiotherapy. Six of the 58 patients submitted to neck dissection had neck recurrence (rate of 10.3%). The only independent prognostic factor for neck recurrence was extracapsular spread. For the 58 patients, the 5-year overall survival was 50% and the disease-specific survival 68.9%. The 5-year disease-specific survival was 76% for pN0 patients and 63.6% for pN+ patients.

CONCLUSIONS:

SND can represent a therapeutic procedure because it has shown oncological results comparable to those of comprehensive neck dissection, especially when SND is combined with adjuvant radiotherapy.

• Authors: Eugenia Allegra, Teresa Franco, Rossana Domanico, Alessandro La Boria, Serena Trapasso, Aldo Garozzo
• Journal: ORL; journal for oto-rhino-laryngology and its related specialties (ORL J Otorhinolaryngol Relat Spec) Vol. 76 Issue 2 Pg. 89-97 ( 2014) ISSN: 1423-0275 [Electronic] Switzerland
• PMID: 24777204 (Publication Type: Journal Article)
• Copyright: © 2014 S. Karger AG, Basel.

Topics

• Carcinoma, Squamous Cell (mortality, pathology, surgery)
• Female
• Head and Neck Neoplasms (mortality, pathology, surgery)
• Humans
• Laryngeal Neoplasms (mortality, pathology, surgery)
• Lymphatic Metastasis
• Male
• Middle Aged
• Neck Dissection (methods)
• Retrospective Studies
• Squamous Cell Carcinoma of Head and Neck
• Treatment Outcome