[Intrauterine therapy for nonimmune hydrops fetalis (NIHF)--analysis of 38 cases].

Abstract

OBJECTIVE:

The aim of the study was to perform an audit the results of fetal therapy in cases of nonimmune hydrops fetalis (NIHF), isolated hydrothorax and isolated ascites.

METHODS:

A total of 38 fetuses (17-35 weeks of pregnancy) were included in the study whereas 6 patients were excluded due to abnormal karyotype. NIHF was diagnosed in 24 cases, hydrothorax in 4 cases, and ascites in 4 cases. Shunts were implanted in 26 (81%) cases and 7 (19%) participants underwent therapeutic cordocentesis.

RESULTS:

After therapy anterior-posterior diameter of the right and the left lung increased to 9.6 mm (27%) and 12.4 mm (35%), respectively. Early complications were observed in 5 (16%) cases. PROM 2 (40%), fetal death 1 (20%), infection 1 (20%), and preterm delivery 1 (20%). Out of the 27 patients, 65% had a caesarian section without early complications and 35% had a vaginal delivery with 58% at term and 42% pre-term.

CONCLUSIONS:

Preceding results show that intrauterine therapy significantly improves prognosis of fetuses with NIHF.

• Authors: Kamila Sobczuk, Justyna Wojtera, Ewa Draga, Ewa Gulczyńska, Katarzyna Janiak, Krzysztof Szaflik
• Journal: Ginekologia polska (Ginekol Pol) Vol. 85 Issue 2 Pg. 92-100 (Feb 2014) ISSN: 0017-0011 [Print] Poland
• Vernacular Title: Terapia wewnatrzmaciczna w nieimmunologicznym obrzeku płodu (NIHF)--analiza 38 przypadków.
• PMID: 24745153 (Publication Type: English Abstract, Journal Article)

Topics

• Cordocentesis (methods)
• Drainage (methods)
• Female
• Humans
• Hydrops Fetalis (surgery)
• Hydrothorax (etiology, surgery)
• Pregnancy
• Pregnancy Outcome
• Pregnancy, High-Risk
• Prenatal Care (methods)
• Ultrasonography, Prenatal