The sympathetic neural hyperalgesia/edema syndrome, a common cause of female pelvic pain, manifesting as a pseudopheochromocytoma with marked clinical improvement with sympathomimetic amines.

Abstract

PURPOSE:

To show that a common but not well-known disorder of the sympathetic nervous system can present with symptoms suggesting a pheochromocytoma.

MATERIALS AND METHODS:

The standard treatment of this disorder (which is characterized by an abnormal water load test), i.e., sympathomimetic amine therapy, was given to a woman with paroxysmal tachycardia and hypertension.

RESULTS:

Over a period of six months, the treatment eradicated the paroxysmal symptoms to which all other therapies had failed.

CONCLUSIONS:

This condition recently named as sympathetic neural hyperalgesia edema syndrome can present with symptoms of a pheochromocytoma and will respond to therapy with low dosages of dextroamphetamine sulfate.

• Authors: J H Check, R Cohen, B Katsoff
• Journal: Clinical and experimental obstetrics & gynecology (Clin Exp Obstet Gynecol) Vol. 41 Issue 1 Pg. 75-7 ( 2014) ISSN: 0390-6663 [Print] Singapore
• PMID: 24707689 (Publication Type: Case Reports, Journal Article)

Chemical References

• Sympathomimetics
• Dextroamphetamine

Topics

• Adenoma (complications)
• Adrenal Gland Neoplasms (complications, diagnosis, drug therapy, physiopathology)
• Adult
• Autonomic Nervous System Diseases (drug therapy, etiology)
• Dextroamphetamine (therapeutic use)
• Diagnosis, Differential
• Edema (etiology, physiopathology)
• Female
• Humans
• Hyperalgesia (diagnosis, etiology, physiopathology)
• Hypertension (complications)
• Pelvic Pain (etiology)
• Pheochromocytoma (diagnosis, drug therapy, physiopathology)
• Sympathomimetics (therapeutic use)
• Syndrome
• Tachycardia (drug therapy, etiology)