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Pseudohypoparathyroidism type II in a woman with a history of thyroid surgery.

Abstract
We herein describe the case of a woman with pseudohypoparathyroidism (PHP) type II. She had a history of subtotal thyroidectomy against Graves' disease without levothyroxine supplementation and presented with stiffness, numbness and muscle cramps. Her surgical history suggested the possibility of secondary hypoparathyroidism; however, the serum intact parathyroid hormone level and results of a Ellsworth-Howard test led to the diagnosis of PHP type II. In the present case, making the differential diagnosis was challenging because two distinct disorders, such as PHP and secondary hypoparathyroidism, may exist simultaneously. This case demonstrates the need to consider the possibility of PHP type II in patients exhibiting hypocalcemia.
AuthorsTakaaki Murakami, Takuo Nambu, Yuki Morimoto, Yuki Matsuda, Koji Matsuo, Shin Yonemitsu, Seiji Muro, Shogo Oki
JournalInternal medicine (Tokyo, Japan) (Intern Med) Vol. 53 Issue 7 Pg. 743-7 ( 2014) ISSN: 1349-7235 [Electronic] Japan
PMID24694489 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Parathyroid Hormone
Topics
  • Aged
  • Diagnosis, Differential
  • Female
  • Graves Disease (surgery)
  • Humans
  • Parathyroid Hormone (blood)
  • Pseudohypoparathyroidism (blood, diagnosis, etiology)
  • Thyroidectomy

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