Treatment outcomes of transurethral macroplastique injection for postprostatectomy incontinence.

Abstract

PURPOSE:

We investigated the efficacy of transurethral injection of Macroplastique bulking agent (Uroplasty) for male stress urinary incontinence (SUI) after prostate surgery.

MATERIALS AND METHODS:

This retrospective review included men with SUI treated by transurethral injection for symptoms resulting from prostate surgery. Patients were evaluated at 1 month and 6 months after injection by determining the number of pads used per day and changes in incontinence symptoms. Treatment success was defined as use of 1 pad or fewer per day combined with subjective symptom improvement.

RESULTS:

The study population comprised 30 men with a mean age of 66.1±5.3 years. Of the 30 patients, 24 (80.0%) underwent prostate cancer surgery and the remaining 6 (20.0%) underwent surgery for benign prostatic hyperplasia. The preinjection pad number was 2.9±1.9 pads per day. After injection treatment, the mean follow-up period was 9.3±12.7 months and the success rate was 43% (13/30) at 1 month and 32% (6/19) at 6 months. Injection was more likely to result in a successful outcome in patients with no preinjection radiation treatment history and higher abdominal leak point pressure (ALPP) than in those with a previous history of radiation treatment and lower ALPP, although this result was not statistically significant. Acute urinary retention occurred in 5 patients (17%).

CONCLUSIONS:

Transurethral Macroplastique injection treatment is a relatively non-invasive treatment method for male SUI with a success rate of 43% at 1 month and 32% at 6 months. Patients with a higher ALPP and no previous history of radiation therapy may experience better treatment outcomes.

• Authors: Sin Woo Lee, Jung Hun Kang, Hyun Hwan Sung, U-Seok Jeong, Young-Suk Lee, Minki Baek, Kyu-Sung Lee
• Journal: Korean journal of urology (Korean J Urol) Vol. 55 Issue 3 Pg. 182-9 (Mar 2014) ISSN: 2005-6737 [Print] Korea (South)
• PMID: 24648873 (Publication Type: Journal Article)