Anti-NMDA receptor encephalitis associated with transient cerebral dyschromatopsia, prosopagnosia, and lack of stereopsis.

Abstract

A 20-year-old woman suffered from anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis and was treated with removal of an ovarian teratoma and retroperitoneal ganglioneuroma in addition to immunotherapy. She was incapable of face recognition, had difficulty with object recognition, and lacked color sensation and stereo perception during recovery. These symptoms were transient and completely resolved over 4 months. Our report documents additional aspects of visual impairment associated with anti-NMDAR encephalitis and suggests that the disease can lead to diffuse cerebral dysfunction including the cortical visual system.

• Authors: Hiromasa Sawamura, Tomotaka Yamamoto, Ryo Ohtomo, Taro Bannai, Masato Wakakura, Shoji Tsuji
• Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society (J Neuroophthalmol) Vol. 34 Issue 2 Pg. 144-8 (Jun 2014) ISSN: 1536-5166 [Electronic] United States
• PMID: 24647141 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Deoxyglucose

Topics

• Anti-N-Methyl-D-Aspartate Receptor Encephalitis (complications)
• Cerebral Cortex (pathology)
• Deoxyglucose
• Depth Perception (physiology)
• Female
• Humans
• Magnetic Resonance Imaging
• Ovarian Neoplasms (complications)
• Perceptual Disorders (complications)
• Positron-Emission Tomography
• Prosopagnosia (complications)
• Teratoma (complications)
• Young Adult