Abstract | OBJECTIVE: MATERIAL AND METHODS: Fifty-one women with PCOS ( Androgen excess society criteria, 2006), with preset inclusion-exclusion criteria, treated with a combination of EE 30 mcg and DRSP 3 mg cyclically in the traditional (21+7) regimen, were evaluated at baseline and after six and twelve cycles of treatment. Parameters studied were - body mass index (BMI), abdominal circumference (AC), Ferriman Galwey (FG) score, presence of acne and acanthosis nigricans, serum testosterone, sex hormone binding globulin (SHBG), fasting glucose and fasting insulin levels. Free Androgen Index (FAI) and Glucose: Insulin ratio (G: I) were calculated. RESULTS: Significant improvements in clinical and biochemical hyperandrogenic parameters were found at the two points of study. There were no significant changes in BMI, AC, incidence of acanthosis, or metabolic parameters studied. CONCLUSION: EE/DRSP improves hyperandrogenic parameters significantly without affecting the insulin resistance adversely in Indian women with PCOS.
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Authors | Sudhindra Mohan Bhattacharya, Mainak Ghosh, Nupur Nandi |
Journal | Journal of the Turkish German Gynecological Association
(J Turk Ger Gynecol Assoc)
Vol. 12
Issue 3
Pg. 144-7
( 2011)
ISSN: 1309-0399 [Print] Turkey |
PMID | 24591981
(Publication Type: Journal Article)
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