Abstract | AIM: To investigate the etiology and clinical characteristics of hypothalamic syndrome in Chinese children. METHODS: Thirty-three cases of hypothalamic syndrome were analyzed for etiology, initial symptoms, and clinical characteristics. RESULTS: All of the 33 patients manifested symptoms of hypothalamic dysfunction and disorders of the hypothalamus-hypophysis-target gland axis. Fourteen patients were diagnosed with an intracranial tumor by magnetic resonance imaging (MRI) examination, four patients had postoperative intracranial tumors, one had received radiotherapy for suprasellar germinoma, one was hypothalamic-pituitary dysplasia, one had a history of viral encephalitis, and in 12 patients, the cause was unknown. The most common presenting symptoms were polydipsia/ polyuria and eating disorders. CONCLUSION:
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Authors | Min Liu, Juan Du, Yanmei Sang, Yujun Wu, Jie Yan, Cheng Zhu |
Journal | Journal of pediatric endocrinology & metabolism : JPEM
(J Pediatr Endocrinol Metab)
Vol. 27
Issue 3-4
Pg. 291-7
(Mar 2014)
ISSN: 2191-0251 [Electronic] Germany |
PMID | 24589760
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Child
- Child, Preschool
- China
- Female
- Humans
- Hypothalamic Diseases
(diagnosis, pathology, therapy)
- Infant
- Magnetic Resonance Imaging
- Male
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