Effective radiotherapy in palliating mammalgia associated with gynecomastia after DES therapy.

Abstract

Between 1977 and 1986, 11 patients with painful gynecomastia after DES therapy were referred for palliative radiotherapy. The treatment regimens varied from 20 Gy in 5 fractions to 40 Gy in 20 fractions. All 11 patients had satisfactory pain relief on follow-up. All 7 patients who had more than 6 months follow-up had complete relief of mammalgia. The average interval between completion of radiotherapy to complete relief of mammalgia was 3.6 months. This study revealed that radiotherapy is highly effective in palliating mammalgia associated with gynecomastia after DES therapy in prostate cancer patients.

• Authors: J L Chou, J D Easley, J J Feldmeier, V A Rauth, T C Pomeroy
• Journal: International journal of radiation oncology, biology, physics (Int J Radiat Oncol Biol Phys) Vol. 15 Issue 3 Pg. 749-51 (Sep 1988) ISSN: 0360-3016 [Print] United States
• PMID: 2458332 (Publication Type: Journal Article)

Chemical References

• Diethylstilbestrol

Topics

• Aged
• Diethylstilbestrol (adverse effects, therapeutic use)
• Gynecomastia (chemically induced, radiotherapy)
• Humans
• Male
• Pain (radiotherapy)
• Palliative Care (methods)
• Prostatic Neoplasms (drug therapy)
• Radiotherapy, High-Energy