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Refractory atrial fibrillation effectively treated with ranolazine.

Abstract
Atrial fibrillation is the most common sustained cardiac arrhythmia which is often troublesome to manage. Currently, rhythm and rate control medications are the mainstays of therapy. In 2 amiodarone-refractory highly symptomatic patients, an innovative approach using ranolazine, which selectively acts on Na+ channels and delays atrial depolarization, was tried successfully.
AuthorsAditi Vaishnav, Avani Vaishnav, Yash Lokhandwala
JournalIndian heart journal (Indian Heart J) 2014 Jan-Feb Vol. 66 Issue 1 Pg. 115-8 ISSN: 2213-3763 [Electronic] India
PMID24581108 (Publication Type: Case Reports, Journal Article, Review)
CopyrightCopyright © 2013 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
Chemical References
  • Acetanilides
  • Piperazines
  • Ranolazine
Topics
  • Acetanilides (administration & dosage)
  • Atrial Fibrillation (diagnosis, drug therapy, etiology)
  • Cardiomyopathy, Hypertrophic (complications, diagnosis)
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Electrocardiography (methods)
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Piperazines (administration & dosage)
  • Ranolazine
  • Recurrence
  • Severity of Illness Index
  • Treatment Outcome

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