Abstract | OBJECTIVE: METHODS: RESULTS: The analgesic effect of HBB as monotherapy is inferior to that of opioids and/or non-steroidal anti-inflammatory drugs ( NSAIDs). It does provide an analgesic and antispasmodic effect, but not as long-lasting as NSAIDs. HBB does not serve as an adjunct to opioids. Furthermore, it does not facilitate passage of ureteral stones and has no effect on expulsion rate. CONCLUSIONS: HBB is often used where urinary tract smooth muscle spasm is thought to be part of the pathophysiological process. According to the evidence, administration of HBB follows non-peer-reviewed protocols which are based on empiric recommendations. Its role is still unclear, as it appears to have no advantage when used as monotherapy over established forms of analgesia. There appears to be a time-dependent relation to pain reduction following parenteral administration, but this needs to be confirmed by more prospective randomized cohorts.
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Authors | George Papadopoulos, Andreas Bourdoumis, Stefanos Kachrilas, Christian Bach, Noor Buchholz, Junaid Masood |
Journal | Urologia internationalis
(Urol Int)
Vol. 92
Issue 3
Pg. 253-7
( 2014)
ISSN: 1423-0399 [Electronic] Switzerland |
PMID | 24576895
(Publication Type: Journal Article, Review)
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Copyright | 2014 S. Karger AG, Basel. |
Chemical References |
- Analgesics
- Muscarinic Antagonists
- Butylscopolammonium Bromide
|
Topics |
- Acute Disease
- Analgesics
(adverse effects, therapeutic use)
- Butylscopolammonium Bromide
(adverse effects, therapeutic use)
- Evidence-Based Medicine
- Humans
- Muscarinic Antagonists
(adverse effects, therapeutic use)
- Renal Colic
(diagnosis, drug therapy)
- Treatment Outcome
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