HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Immunohistochemical localization of keratin, vimentin and myosin in salivary gland tumors.

Abstract
An immunohistochemical study on keratin, vimentin, and myosin was performed in 117 specimens of human salivary gland under normal and several neoplastic conditions. In normal glands, positive immunostaining for keratin was observed in the inner cells of all ductal systems, whereas myosin and vimentin were the cytoskeletal components of myoepithelial cells. In pleomorphic adenoma, the inner cells showing a tubular pattern demonstrated positive immunostaining for keratin, and the outer cells as well as the neoplastic cells with a solid and myxoid pattern exhibited positive immunostaining for all antibodies. Monomorphic tubular and trabecular adenoma, and adenolymphoma showed positive immunostaining for keratin, although one case of tubular adenoma exhibited positive immunostaining for all antibodies. Squamous cell carcinoma, adenosquamous carcinoma, and mucoepidermoid tumor showed positive immunostaining only for keratin, but one case of adenocarcinoma, two cases of adenoid cystic carcinoma, and clear cell tumor disclosed positive immunostaining for keratin and vimentin.
AuthorsR Matsushima, I Nakayama, M Shimizu
JournalActa pathologica japonica (Acta Pathol Jpn) Vol. 38 Issue 4 Pg. 445-54 (Apr 1988) ISSN: 0001-6632 [Print] JAPAN
PMID2456668 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Vimentin
  • Keratins
  • Myosins
Topics
  • Adenoma (metabolism, pathology)
  • Humans
  • Immunoenzyme Techniques
  • Immunohistochemistry
  • Keratins (metabolism)
  • Myosins (metabolism)
  • Salivary Gland Neoplasms (metabolism, pathology)
  • Salivary Glands (cytology, metabolism)
  • Vimentin (metabolism)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: