Nephrolithiasis by Corynebacterium urealyticum infection: literature review and case report.

Abstract

INTRODUCTION:

Alkaline-encrusted cystitis or pyelonephritis is a chronic inflammatory condition due to deposition of crystals usually caused by urea-splitting bacteria. Corynebacterium urealyticum (CU) is a gram-positive, urea-splitting and multi-antibiotic resistant bacillus with special tropism for the urinary tract and it is often associated with encrusted pyelocystitis.

METHODS AND RESULTS:

Here we report the case of a 75-year-old Caucasian man with a prolonged history of renal stones who was admitted for gross hematuria associated with renal failure. A diagnosis of encrusted pyelocystitis due to CU infection was made and the patient was appropriately treated.

CONCLUSIONS:

At 6-month follow-up the patient was in good general conditions and asymptomatic. Signs of urinary tract infection or of renal calculosis were still detectable.

• Authors: Laura Cappuccino, Paolo Bottino, Adele Torricella, Roberto Pontremoli
• Journal: Journal of nephrology (J Nephrol) Vol. 27 Issue 2 Pg. 117-25 (Apr 2014) ISSN: 1724-6059 [Electronic] Italy
• PMID: 24563271 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Anti-Bacterial Agents

Topics

• Aged
• Anti-Bacterial Agents (therapeutic use)
• Corynebacterium Infections (diagnosis, drug therapy)
• Humans
• Male
• Nephrolithiasis (diagnosis, microbiology, therapy)
• Nephrostomy, Percutaneous
• Pyelocystitis (diagnosis, microbiology, therapy)
• Stents
• Therapeutic Irrigation