Abstract |
A 63-year-old man with multiple HCC in his left liver lobe was enrolled as the first patient in a pilot study of boron neutron capture therapy (BNCT) involving the selective intra-arterial infusion of a (10)BSH-containing water-in-oil-in-water emulsion ((10)BSH-WOW). The size of the tumorous region remained stable during the 3 months after the BNCT. No adverse effects of the BNCT were observed. The present results show that (10)BSH-WOW can be used as novel intra-arterial boron carriers during BNCT for HCC.
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Authors | Hironobu Yanagie, Syushi Higashi, Koji Seguchi, Ichiro Ikushima, Mituteru Fujihara, Yasumasa Nonaka, Kazuyuki Oyama, Syoji Maruyama, Ryo Hatae, Minoru Suzuki, Shin-ichiro Masunaga, Tomoko Kinashi, Yoshinori Sakurai, Hiroki Tanaka, Natsuko Kondo, Masaru Narabayashi, Tetsuya Kajiyama, Akira Maruhashi, Koji Ono, Jun Nakajima, Minoru Ono, Hiroyuki Takahashi, Masazumi Eriguchi |
Journal | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
(Appl Radiat Isot)
Vol. 88
Pg. 32-7
(Jun 2014)
ISSN: 1872-9800 [Electronic] England |
PMID | 24559940
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2014 Elsevier Ltd. All rights reserved. |
Chemical References |
- Borohydrides
- Emulsions
- Oils
- Sulfhydryl Compounds
- Water
- mercaptoundecahydrododecaborate
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Topics |
- Borohydrides
(administration & dosage, chemistry)
- Boron Neutron Capture Therapy
(methods)
- Carcinoma, Hepatocellular
(diagnosis, radiotherapy)
- Emulsions
(administration & dosage, chemistry)
- Humans
- Injections, Intra-Arterial
- Liver Neoplasms
(diagnosis, radiotherapy)
- Male
- Middle Aged
- Neoplasm Recurrence, Local
(diagnosis, radiotherapy)
- Oils
(chemistry)
- Pilot Projects
- Sulfhydryl Compounds
(administration & dosage, chemistry)
- Treatment Outcome
- Water
(chemistry)
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