Preoperative evaluation of colorectal liver metastases: comparison of gadopentetate dimeglumine and gadoxetic-acid-enhanced 1.5-T MRI.

Abstract

PURPOSE:

The aim of this study was to compare the diagnostic performance of gadopentetate dimeglumine and gadoxetic-acid-enhanced MRI in patients with colorectal liver metastases.

METHODS:

Thirty patients were included and divided into three sets, as follows: gadopentetate dimeglumine set-hepatic arterial phase, portal venous phase, and delay phase; gadoxetic acid set-hepatic arterial phase, portal venous phase, and delay phase; combined set-gadoxetic acid set and hepatobiliary phase. The accuracy was assessed by the area under the alternative-free response receiver operating characteristic curve; the sensitivity and positive predictive value were calculated.

RESULTS:

There were 81 colorectal liver metastases in all. Both readers noted higher diagnostic accuracies of the combined set than the other two sets. In the group of small lesions, both readers detected significantly higher sensitivities and positive predictive value on the combined set than the other two sets.

CONCLUSIONS:

The combined set showed higher accuracy and sensitivity, especially significantly higher accuracy and sensitivity on small lesions.

• Authors: Ying Ding, Sheng-Xiang Rao, Tao Meng, Caizhong Chen, Renchen Li, Meng-Su Zeng
• Journal: Clinical imaging (Clin Imaging) 2014 May-Jun Vol. 38 Issue 3 Pg. 273-8 ISSN: 1873-4499 [Electronic] United States
• PMID: 24559747 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2014 Elsevier Inc. All rights reserved.

Chemical References

• Contrast Media
• gadolinium ethoxybenzyl DTPA
• Gadolinium DTPA

Topics

• Adult
• Aged
• Colorectal Neoplasms (secondary, surgery)
• Contrast Media
• Female
• Gadolinium DTPA
• Humans
• Liver Neoplasms (pathology)
• Magnetic Resonance Imaging (methods, statistics & numerical data)
• Male
• Middle Aged
• Preoperative Care
• ROC Curve
• Sensitivity and Specificity