Efficacy assessment of newly developed open-window intervention needles for the treatment of cystic thyroid nodules that cannot be aspirated.

Abstract

OBJECTIVE:

The purpose of this study was to develop a novel open-window needle aspiration method and evaluate its efficacy in drainage and sclerotherapy of cystic thyroid nodules that cannot be aspirated with an 18-gauge needle.

METHODS:

Two rectangular windows 5.0 mm in length and 1.0 mm wide were placed at the end of the percutaneous transhepatic cholangiography (PTCA) needle trocar to develop a new open-window intervention needle. The efficiency of the open-window intervention needle was compared either to a porous interventional needle or to an ordinary PTCA needle by assessing the aspiration efficiency. The efficacy of the modified open-window approach was tested by carrying out sclerotherapy and drainage on 21 thyroid cystic nodules that could not be aspirated with an 18-gauge needle and comparing it to aspiration with an 18-gauge PTCA needle of 50 cystic thyroid nodules.

RESULTS:

The efficacy of aspirating coupling agents of various specifications using the new open-window intervention was superior to aspiration using the PTCA trocar needle or a porous needle (p<0.05). Ethanol ablation efficacy in the treatment of 21 cystic thyroid nodules that could not be aspirated with an 18-gauge needle and the aspiration efficacy of 50 cystic thyroid nodules with an 18-gauge PTCA needle were not significantly different (p>0.05).

CONCLUSION:

The new open-window intervention needle approach was highly effective in conducting ethanol ablation of cystic thyroid nodules that could not be aspirated using conventional methodologies.

• Authors: Guorong Lv, Shaohua Chen, Boyi Li, Xiaokang Chen, Shilin Li
• Journal: Thyroid : official journal of the American Thyroid Association (Thyroid) Vol. 24 Issue 6 Pg. 1012-7 (Jun 2014) ISSN: 1557-9077 [Electronic] United States
• PMID: 24547900 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Ethanol

Topics

• Adult
• Biopsy, Needle (instrumentation)
• Cysts (diagnostic imaging, drug therapy)
• Ethanol (administration & dosage)
• Female
• Humans
• Injections, Intralesional
• Male
• Middle Aged
• Sclerotherapy (methods)
• Thyroid Nodule (diagnostic imaging, therapy)
• Ultrasonography