HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

A hydrosurgery system (Versajet) with and without hydrogen peroxide solutions for the debridement of subacute and chronic wounds: a comparative study with hydrodebridement.

AbstractOBJECTIVE:
The aim of this study was to evaluate the efficacy of hydrosurgery prepared with or without hydrogen peroxide for the management of subacute and chronic wounds.
METHODS:
This is a retrospective study on patients with infected subacute and chronic wounds. The wounds were debrided using hydrosurgery prepared with (the study group) or without hydrogen peroxide before grafting the wound (the control group).
RESULTS:
There were 60 patients in the study group and 70 patients in the control group. The hospital stay (mean, 7.83 [SD, 2.16] vs 9.86 [SD, 3.41] days; P < .001) and graft viability (mean, 3 [2-3] vs 2 [2-3]; P = .001) were significantly better in the study group than in the control group. The difference of hemoglobin levels after surgery was also significantly lower in the study group (0.1 [0-0.48] vs 0.45 [0-1]; P = .004).
CONCLUSIONS:
Encouraging results were obtained with the use of the hydrosurgery system prepared with hydrogen peroxide for infected subacute and chronic wounds. This method decreased hospital stay and bleeding, thus providing better contact of the skin graft with the wound bed, allowing early rehabilitation. The findings of the authors' study need to be substantiated in large-scale randomized controlled trials.
AuthorsSaime Irkoren, Nazan Sivrioglu
JournalAdvances in skin & wound care (Adv Skin Wound Care) Vol. 27 Issue 3 Pg. 127-31 (Mar 2014) ISSN: 1538-8654 [Electronic] United States
PMID24531519 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Water
  • Hydrogen Peroxide
Topics
  • Acute Disease
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Chronic Disease
  • Debridement (instrumentation, methods)
  • Female
  • Graft Survival
  • Humans
  • Hydrogen Peroxide (therapeutic use)
  • Infant
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Assessment
  • Skin Transplantation (methods)
  • Statistics, Nonparametric
  • Treatment Outcome
  • Turkey
  • Water (administration & dosage)
  • Wound Healing (physiology)
  • Wounds and Injuries (diagnosis, surgery)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: