Kasai hepatoportoenterostomy in South Australia: a case for 'centralized decentralization'.
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| Abstract | BACKGROUND: Recent follow-up studies have demonstrated significant improvement in overall survival as well as survival with native liver following geographic centralization of services to three centres in the UK. However, this model has not been replicated in countries with relatively low population density such as Australia and Canada. METHODS: Retrospective evaluation of all patients born with biliary atresia (BA) in South Australia from 1989 to 2010 was performed. Thirty-one patients with BA were discovered. Two patients were excluded because the initial Kasai procedure (KP) was performed interstate. Outcome parameters measured were (i) clearance of jaundice (bilirubin of less than 20 μmol/L, by 6 months); (ii) survival with native liver; and (iii) overall survival. Kaplan-Meier survival curves were plotted for both survival with native liver and overall survival. RESULTS: The incidence of BA in South Australia between 1989 and 2010 was 7.48 per 100,000 live births. Following KP, clearance of jaundice was achieved in 42.9% of patients. Five-year actuarial survival with native liver was 55.2%, and overall 5-year actuarial survival was 89.3%. CONCLUSIONS: The results of KP performed at Women's and Children's Hospital from 1989 to 2010 can be considered comparable with international benchmarks. Based on these results, we propose the creation of a 'centralized' pool of surgeons in Australia to help continue providing 'decentralized' care of BA.
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| Authors | Chen Gang Tu, Sanjeev Khurana, Richard Couper, Andrew W D Ford |
| Journal | ANZ journal of surgery (ANZ J Surg) Vol. 85 Issue 11 Pg. 865-8 (Nov 2015) ISSN: 1445-2197 [Electronic] Australia |
| PMID | 24529070 (Publication Type: Journal Article) |
| Copyright | © 2014 Royal Australasian College of Surgeons. |
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