Abstract | BACKGROUND: METHODS: RESULTS: The glucose regulation worsened and insulin dose increased in patients with diabetes, which was notably seen during the steroid maintenance period. Following steroid withdrawal, however, there was a decrease in the insulin dose in 55.6% of the patients, and 33.3% of the patients converted from insulin to oral agents. Of the patients with prediabetes, 55.3% developed new-onset diabetes after transplantation (NODAT). However, 18.4% achieved a recovery of glucose levels to normal range. Of the 21 NODAT patients, 52.4% achieved a recovery of glucose level to the prediabetes range after steroid withdrawal. There was a significant correlation between the old age and the persistence of NODAT (P < .05). CONCLUSIONS: LT may have a diverse effect on glycemia, which may lead to changes in glucose control methods. Therefore, glucose metabolism after LT may need to be differentiated by the underlying glucose disturbance status and the time after LT with or without steroid maintenance period.
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Authors | S H Kim, J M Kim, K A Lee, T S Park, H S Baek, H C Yu, H Y Jin |
Journal | Transplantation proceedings
(Transplant Proc)
2014 Jan-Feb
Vol. 46
Issue 1
Pg. 225-9
ISSN: 1873-2623 [Electronic] United States |
PMID | 24507056
(Publication Type: Journal Article, Observational Study)
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Copyright | Copyright © 2014 Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Blood Glucose
(analysis)
- Cross-Sectional Studies
- Diabetes Complications
(therapy)
- Diabetes Mellitus, Type 2
(blood, complications)
- Female
- Glucose Tolerance Test
- Humans
- Insulin
(blood)
- Liver Failure
(blood, complications, surgery)
- Liver Transplantation
- Longitudinal Studies
- Male
- Middle Aged
- Prediabetic State
(blood, complications)
- Retrospective Studies
- Treatment Outcome
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