Ethanol embolotherapy of vascular malformations: clinical outcomes at a single center.

Abstract

PURPOSE:

To retrospectively evaluate the results of endovascular therapy of vascular malformations principally treated with ethanol embolization at a single center.

MATERIALS AND METHODS:

From May 1999 to December 2012, 46 patients (28 female, 18 male) with vascular malformations (31 venous malformations, 15 arteriovenous malformations [AVMs]) throughout the body (nine upper extremity, 31 lower extremity, and six truncal) who underwent ethanol embolization were studied and followed up. Demographic factors, clinical findings, imaging data, and patient-reported changes in symptoms were collected and analyzed. Follow-up data were obtained by office visits, repeat imaging, and telephone contact.

RESULTS:

Twenty-four patients (52.2%) were considered cured, 12 (26.1%) showed improvement, and 10 (21.7%) had no change or showed worsening. Similar rates of cure or improvement were seen for AVMs and venous malformations (P = 0.67). Lesion location, depth, and size were not associated with differences in outcomes (P = .87, P = .37, and P = .61, respectively). Type 1 and type 2 AVMs were cured more often than other AVM types. The overall complication rate was 24% (11 of 46 patients). Minor complications were seen in six individuals (13%), and major complications developed in five patients (11%).

CONCLUSIONS:

Ethanol embolization of vascular malformations produces good outcomes, with control or relief of symptoms in a majority of patients.

• Authors: Robert L Vogelzang, Rohi Atassi, Michael Vouche, Scott Resnick, Riad Salem
• Journal: Journal of vascular and interventional radiology : JVIR (J Vasc Interv Radiol) Vol. 25 Issue 2 Pg. 206-13; quiz 214 (Feb 2014) ISSN: 1535-7732 [Electronic] United States
• PMID: 24461130 (Publication Type: Journal Article)
• Copyright: © 2014 SIR Published by SIR All rights reserved.

Chemical References

• Ethanol

Topics

• Adolescent
• Adult
• Aged
• Embolization, Therapeutic (adverse effects, methods)
• Endovascular Procedures (adverse effects, methods)
• Ethanol (administration & dosage, adverse effects)
• Female
• Humans
• Magnetic Resonance Angiography
• Male
• Middle Aged
• Retrospective Studies
• Time Factors
• Treatment Outcome
• Vascular Malformations (diagnosis, therapy)
• Young Adult