Abstract |
In this issue of Blood, Zhang et al describe an exciting new small-molecule antagonist of CXCL12-CXCR4 binding with a potent ability to mobilize hematopoietic stem cells (HSCs). Further clinical development of this new drug, Me6TREN, may have broad applications in stem-cell mobilization for cancer and in regenerative medicine.
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Authors | Sakura Hosoba, Edmund K Waller |
Journal | Blood
(Blood)
Vol. 123
Issue 3
Pg. 310-1
(Jan 16 2014)
ISSN: 1528-0020 [Electronic] United States |
PMID | 24434996
(Publication Type: Journal Article, Comment)
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Chemical References |
- Ethylamines
- tris(2-(dimethylamino)ethyl)amine
|
Topics |
- Animals
- Ethylamines
(pharmacology)
- Gene Expression Regulation
- Hematopoietic Stem Cell Mobilization
(methods)
- Hematopoietic Stem Cells
(cytology)
- Humans
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