Abstract | OBJECTIVE: METHODS: RESULTS: After 9 months of treatment, all the 12 patients showed significant improvement in the penile length, testicular volume and sex hormone levels (P < 0.01), with different degrees of promotion of the secondary sexual development. Three married cases could have normal sexual intercourse, and one of them achieved normal pregnancy. CONCLUSION: The clinical characteristics of Kallmann syndrome include lack of gonadotropins, lower gonad function and loss or reduction of olfactory sensation. Replacement therapy with hCG, hMG and androgens is an effective treatment method. However, no effective therapy is now available for olfactory dysfunction. Early diagnosis and hormone replacement therapy can best alleviate its clinical symptoms and eventually achieve fertility.
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Authors | Wei Gong, Xing-Cheng Gao |
Journal | Zhonghua nan ke xue = National journal of andrology
(Zhonghua Nan Ke Xue)
Vol. 19
Issue 12
Pg. 1111-4
(Dec 2013)
ISSN: 1009-3591 [Print] China |
PMID | 24432625
(Publication Type: English Abstract, Journal Article)
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Topics |
- Adolescent
- Adult
- Hormone Replacement Therapy
- Humans
- Kallmann Syndrome
(diagnosis, drug therapy)
- Male
- Retrospective Studies
- Young Adult
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