Abstract | OBJECTIVE: METHODS:
Amino acids were extracted from plasma and measured using ultra performance liquid chromatography mass spectrometry. RESULTS: Plasma alloisoleucine was 238% higher in obese compared to lean Zucker rats. This elevation was greater than that of other BCAAs (107-124%). DIO rats had no significant change in alloisoleucine, despite elevations in other BCAAs (15-66%). CONCLUSIONS:
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Authors | Kristine C Olson, Gang Chen, Yuping Xu, Andras Hajnal, Christopher J Lynch |
Journal | Obesity (Silver Spring, Md.)
(Obesity (Silver Spring))
Vol. 22
Issue 5
Pg. 1212-5
(May 2014)
ISSN: 1930-739X [Electronic] United States |
PMID | 24415721
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Copyright | Copyright © 2014 The Obesity Society. |
Chemical References |
- Isoleucine
- 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
|
Topics |
- 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
(metabolism)
- Adipose Tissue
(metabolism)
- Amino Acid Metabolism, Inborn Errors
(blood)
- Animals
- Chromatography, Liquid
- Diet, High-Fat
- Isoleucine
(blood)
- Male
- Obesity
(blood)
- Rats
- Rats, Zucker
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