Clarithromycin induced psoriasis in a 37-year old man.

Abstract

Many drugs may induce psoriatic lesions or exacerbate preexisting psoriasis. We report an exceptional case of psoriasis vulgaris probably induced by clarithromycin. A 37-year-old man was prescribed for pharyngitis clarithromycin 500mg twice a day. On the third day of treatment, he presented a non pruriginous erythemato-squamous eruption, of trunk and limbs. Skin biopsy showed a typical aspect of psoriasis vulgaris. The drug was interrupted and the patient was treated by topical corticoids with rapid improvement.

• Authors: Ahmed Zaiem, Amel Mebazaa, Ghozlane Lakhoua, Talel Badri, Rym Sahnoun, Sarrah Kastalli, Riadh Daghfous, Sihem El Aidli
• Journal: Current drug safety (Curr Drug Saf) Vol. 9 Issue 1 Pg. 77-8 (Mar 2014) ISSN: 2212-3911 [Electronic] United Arab Emirates
• PMID: 24410388 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anti-Inflammatory Agents
• Betamethasone
• Clarithromycin

Topics

• Administration, Topical
• Adult
• Anti-Bacterial Agents (adverse effects)
• Anti-Inflammatory Agents (administration & dosage, therapeutic use)
• Betamethasone (administration & dosage, therapeutic use)
• Clarithromycin (adverse effects)
• Drug Eruptions (pathology)
• Humans
• Male
• Psoriasis (chemically induced)
• Skin (pathology)